Registrar's Reading Lists

For many neurological conditions there are guidelines and expert statements available. Journals focus on trainees teaching topics (e.g. practical neurology). Furthermore, there are many reviews on clinical issues of variable quality.

The aim is to build a reading list of high-quality and up-to-date reviews on core neurology curriculum areas for registrars across Europe. The focus should be clinical and practical, to guide neurology trainees learning their trade in optimal standards of diagnosis, investigation and management in daily clinical practice.

 

You can find below a list of reviews, recommended by the EAN Scientific Panels.

Bedside Approach to Autonomic Disorders?

Bedside Approach to Autonomic Disorders? A clinical Tutor, edited by Walter Struhal, Heinz Lahrmann, Alessandra Fanciulli and Gregor K.Wenning. Springer Verlag, 2017.

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Multiple System Atrophy

Multiple System Atrophy, edited by Gregor K. Wenning & Alessandra Fanciulli. Springer Verlag, 2014.

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Primer of the Autonomic Nervous System

Robertson D, Biaggioni I, Burnstock G, Low PA, Paton JFR, eds. Primer of the Autonomic Nervous System, Academic Press, Oxford, 2012

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Clinical Autonomic Disorders

Low PA., Benarroch EE, eds.: Clinical Autonomic Disorders, Third Edition. Lippincott Williams & Wilkins, Philadelphia, 2008

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Neurourology: Theory and Practice.

Neurourology: Theory and Practice.  Editors: Liao, Limin, Madersbacher, Helmut (Eds.).  Springer 2019

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Stålberg E, van Dijk H, Falck B, Kimura J, Neuwirth C, Pitt M, Podnar S, Rubin DI, Rutkove S, Sanders DB, Sonoo M, Tankisi H, Zwarts M: Standards for quantification of EMG and neurography, Clinical Neurophysiology 2019, Issue 19

Mamede de Carvalho; Matthew Kiernan; Michael Swash: Fasciculation; Amyotrophic lateral sclerosis; benign fasciculation syndrome, Journal of Neurology, Neurosurgery and Psychiatry 2017, Issue 88

Anders Fuglsang-Friederiksen; Kirsten Pugdahl: Current status on electrodiagnostic standards and guidelines in neuromuscular disorders, Clinical Neurophysiology 2011, Issue 122

RK Olney: Clinical Trials for Polyneuropathy: The Role of Nerve Conduction Studies, Quantitative Sensory Testing, and Autonomic Function Testing, Journal of clinical neurophysiology 1998, Issue 15

Josep Valls-Sole: Facial nerve palsy and hemifacial spasm, Handbook of clinical neurophysiology 2013, Issue 115

 

Papathanasiou ES, Straumann D. Why and When to Refer Patients for Vestibular Evoked Myogenic Potentials: A Critical Review. Clin Neurophysio2019;130:1539-1556

 

Jean-Pascal Lefaucheur, Andrea Antal, Samar S. Ayache, David H. Benninger, Jérôme Brunelin, Filippo Cogiamanian, Maria Cotelli, Dirk De Ridder, Roberta Ferrucci, Berthold Langguth, Paola Marangolo, Veit Mylius, Michael A. Nitsche, Frank Padberg, Ulrich Palm, Emmanuel Poulet, Alberto Priori, Simone Rossi, Martin Schecklmann, Sven Vanneste, Ulf Ziemann, Luis Garcia-Larrea, Walter Paulus: Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS), Clinical Neurophysiology 2017, Issue 128 (1)

Tatum WO, Rubboli G, Kaplan PW, Mirsatari SM, Radhakrishnan K, Gloss D, Caboclo LO, Drislane FW, Koutroumanidis M, Schomer DL, Kasteleijn-Nolst Trenite D, Cook M, Beniczky S: Clinical utility of EEG in diagnosing and monitoring epilepsy in adults, Clinical Neurophysiology 2018, Issue 129(5)

Bowley MP, Chad DA: Clinical neurophysiology of demyelinating polyneuropathy, Handbook of clinical neurology 2019, Volume 161

 P.M. Rossini, D. Burke, R. Chen, L.G. Cohen, Z. Daskalakis, R. Di Iorio, V. Di Lazzaro, F. Ferreri, P.B. Fitzgerald, M.S. George, M. Hallett, J.P. Lefaucheur, B. Langguthm, H. Matsumoton, C. Miniussi, M.A. Nitsche, A. Pascual-Leone, W. Paulus, S. Rossi, J.C. Rothwell, H.R. Siebner, Y. Ugawa, V. Walsh, and U. Ziemann: Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee, Clinical Neurophysiology 2015, Issue 126(6)

Emmanuel Fournier, Nacira Tabti: Clinical electrophysiology of muscle diseases and episodic muscle disorders, Handbook of clinical neurology 2019, Volume 161

Muzyka IM, Estephan B: Somatosensory evoked potentials, Handbook of clinical neurology 2019, Volume 160

 

 

Ben M.W. Illigens, Christopher H. Gibbons: Autonomic testing; Autonomic reflex testing; ANS; Tilt table testing; Head-up tilt; HUT; Sudomotor; Sweat testing; Pilomotor; Vasomotor; QSART ;Thermoregulatory; sweat testing; TST, Handbook of clinical neurology 2019, Volume 160,  PMID: 31277866

Johnson EL, Kaplan PW: Clinical neurophysiology of altered states of consciousness: Encephalopathy and coma, Handbook of clinical neurology 2019, Volume 161

Sanders DB, Arimura K, Cui L, Ertaş M, Farrugia ME, Gilchrist J, Kouyoumdjian JA, Padua L, Pitt M, Stålberg E: Guidelines for single fiber EMG, Clinical Neurophysiology 2019, Volume 130

Tremblay S, Rogasch NC, Premoli I, Blumberger DM, Casarotto S, Chen R, Di Lazzaro V, Farzan F, Ferrarelli F, Fitzgerald PB, Hui J, Ilmoniemi RJ, Kimiskidis VK, Kugiumtzis D, Lioumis P, Pascual-Leone A, Pellicciari MC, Rajji T, Thut G, Zomorrodi R, Ziemann U, Daskalakis ZJ: Clinical utility and prospective of TMS-EEG, Clinical Neurophysiology 2019, Volume 130(5)

Garcia-Larrea L, Hagiwara K.: Electrophysiology in diagnosis and management of neuropathic pain, Rev Neurol 2018, Volume 175

MacDonald DB, Dong C, Quatrale R, Sala F, Skinner S, Soto F, Szelényi A: Recommendations of the International Society of Intraoperative Neurophysiology for intraoperative somatosensory evoked potentials, Clinical Neurophysiology 2019, Volume 130(1)

Fatehi F, Grapperon AM, Fathi D, Delmont E, Attarian S.: The utility of motor unit number index: A systematic review, Neurophysiologie Clinique 2018, Volume 48(5)

Roberts MM: Neurophysiology in neurourology, Muscle and Nerve 2018, Volume 38(1)

Krieg SM, Lioumis P, Mäkelä JP, Wilenius J, Karhu J, Hannula H, Savolainen P, Lucas CW, Seidel K, Laakso A, Islam M, Vaalto S, Lehtinen H, Vitikainen AM, Tarapore PE, Picht T.: Protocol for motor and language mapping by navigated TMS in patients and healthy volunteers; workshop report, Acta Neurochirurgica, Volume 159(7)

Rossini PM, Di Iorio R, Bentivoglio M, Bertini G, Ferreri F, Gerloff C, Ilmoniemi RJ, Miraglia F, Nitsche MA, Pestilli F, Rosanova M, Shirota Y, Tesoriero C, Ugawa Y, Vecchio F, Ziemann U, Hallett M.: Methods for analysis of brain connectivity: An IFCN-sponsored review, Clinical Neurophysiology 2019, Volume 130(10

Dementia and Cognitive Disorders

A Systematic Review of Practice Guidelines and Recommendations for Discontinuation of Cholinesterase Inhibitors in Dementia.

The cognitive profile of behavioural variant FTD and its similarities with ALS: a systematic review and meta-analysis.

 

Subjective cognitive decline (SCD)

A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease. Alzheimers Dement 

Subjective cognitive decline and rates of incident Alzheimer's disease and non-Alzheimer's disease dementia

Italian consensus recommendations for a biomarker-based aetiological diagnosis in mild cognitive impairment patients.

 

Alzheimer´s disease (AD)

 

Mild cognitive impairment due to AD (MCI)

The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.

AD dementia

Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers.

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease.

Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers.

AD dementia treatment

EFNS-ENS/EAN Guideline on concomitant use of cholinesterase inhibitors and memantine in moderate to severe Alzheimer's disease.

A European Academy of Neurology guideline on medical management issues in dementia.

Current understanding of Alzheimer's disease diagnosis and treatment.

Treatment Combinations for Alzheimer's Disease: Current and Future Pharmacotherapy Options.

Management of mild cognitive impairment (MCI): The need for national and international guidelines.

 

Atypical forms of AD

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria.

Posterior cortical atrophy

Posterior cortical atrophy.

Frontal variant AD

Diagnosing the frontal variant of Alzheimer's disease: a clinician's yellow brick road.

Logopenic aphasia

Classification of primary progressive aphasia and its variants.

 

Differential diagnosis of dementia

EFNS-ENS Guidelines on the diagnosis and management of disorders associated with dementia.

Consensus guidelines for lumbar puncture in patients with neurological diseases.

Recommendations for cerebrospinal fluid Alzheimer's disease biomarkers in the diagnostic evaluation of mild cognitive impairment.

Recommendations for CSF AD biomarkers in the diagnostic evaluation of dementia.

European Association of Nuclear Medicine and European Academy of Neurology recommendations for the use of brain (18) F-fluorodeoxyglucose positron emission tomography in neurodegenerative cognitive impairment and dementia: Delphi consensus.

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.

Autoimmune Encephalitides and Rapidly Progressive Dementias.

Primary age-related tauopathy (PART): a common pathology associated with human aging.

 

Dementia with Lewy bodies (DLB)

Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium.

Research criteria for the diagnosis of prodromal dementia with Lewy bodies.

 

Frontotemporal  dementia

Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia.

Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine.

 

Primary Progressive aphasia (PPA)

Classification of primary progressive aphasia and its variants.

 

Vascular cognitive impairment

Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study.

 

Cognitive deficit in Parkinson´s disease

Cognition Deficits in Parkinson's Disease: Mechanisms and Treatment.

 

Cognitive deficit in multiple system atrophy

Cognitive impairment in multiple system atrophy: a position statement by the Neuropsychology Task Force of the MDS Multiple System Atrophy (MODIMSA) study group.

 

Cognitive deficit in Corticobasal syndrome (CBS) and progressive supranuclear palsy (PSP)

Cognition in corticobasal syndrome and progressive supranuclear palsy: a review.

Ferrari MD, Klever RR, Terwindt GM, Ayata C, van den Maagdenberg AM. Migraine pathophysiology: lessons from mouse models and human genetics. Lancet Neurol, 2015 Issue 14

Goadsby PJ, Holland PR, Martins-Oliveira M, Hoffmann J, Schankin C, Akerman S. Pathophysiology of Migraine: A Disorder of Sensory Processing. Physiol Rev 2017, Issue 97

Hoffmann J, May A. Diagnosis, pathophysiology, and management of cluster headache. Lancet Neurol  2018, Issue 17

Bendtsen L, Jensen R. Tension-type headache. Neurol Clin 2009, Issue 27

Steiner TJ, Stovner LJ, Vos T. GBD 2015: migraine is the third cause of disability in under 50s. J Headache Pain, 2016, Issue 17

Jensen R, Stovner LJ. Epidemiology and comorbidity of headache. Lancet Neurol  2008, Issue 7

Evers S, Marziniak M. Clinical features, pathophysiology, and treatment of medication-overuse headache. Lancet Neurol 2010, Issue 9

Zakrzewska JM, Linskey ME. Trigeminal neuralgia. BMJ 2015, Issue 350

Gelfand AA. Migraine and childhood periodic syndromes in children and adolescents. Curr Opin Neurol  2013, Issue 26

Antonaci F, Voiticovschi-Iosob C, Di Stefano AL, Galli F, Ozge A, Balottin U. The evolution of headache from childhood to adulthood: a review of the literature. J Headache Pain 2014, Issue 15

Kipps CM, Hodges JR. Cognitive assessment for cliniciansJournal of Neurology, Neurosurgery & Psychiatry 2005;76:i22-i30

PMID: 15718218

Zucchella C, Federico A, Martini A, et al. Neuropsychological testingPractical Neurology 2018;18:227-237, PMID: 29472384

Goldberg G Apraxia. Wiley Interdiscip Rev Cogn Sci. 2013; 4: 453-462
PMID: 26304239

Dovern, A., Fink, G.R. & Weiss, P.H. J Neurol (2012) 259: 1269.
PMID: 22215235

Rode G, Pagliari C, Huchon L, Rossetti Y, Pisella L. Semiology of neglect: An update. Annals of Physical and Rehabilitation Medicine. Volume 60, Issue 3, June 2017, Pages 177-185.
PMID: 27103056

Gainotti G, Trojano L. Constructional apraxia. Handbook of Clinical Neurology. 2018: 151; 331-348
PMID: 29519467

O'Sullivan M, Brownsett S, Copland DLanguage and language disorders: neuroscience to clinical practicePractical Neurology 2019;19:380-388
PMID: 31350297

Budson A, Price B. Primitive plaques and memory dysfunction in normal and impaired elderly persons. Practical Neurology. 2007: 7; 42-47
PMID: 17430864

Reid S, Thompson H, Thakur KT. Nervous System Infections and the Global Traveler. Semin Neurol. 2018;38(2):247-262. doi:10.1055/s-0038-1649335

Sigfrid L, Perfect C, Rojek A, et al. A systematic review of clinical guidelines on the management of acute, community-acquired CNS infectionsBMC Med. 2019;17(1):170. Published 2019 Sep 6. doi:10.1186/s12916-019-1387-5

Thakur KT, Boubour A, Saylor D, Das M, Bearden DR, Birbeck GL. Global HIV neurology: a comprehensive review. AIDS. 2019;33(2):163-184. doi:10.1097/QAD.0000000000001796

 

Autoimmune Encephalitis

Dalmau J, Graus F. Antibody-Mediated Encephalitis. N Engl J Med. 2018 Mar1;378(9):840-851. doi: 10.1056/NEJMra1708712.

Hermetter C, Fazekas F, Hochmeister S. Systematic Review: Syndromes, Early Diagnosis, and Treatment in Autoimmune Encephalitis. Front Neurol. 2018 Sep5;9:706. doi: 10.3389/fneur.2018.00706.

Dalmau J, Armangué T, Planagumà J, Radosevic M, Mannara F, Leypoldt F, Geis C, Lancaster E, Titulaer MJ, Rosenfeld MR, Graus F. An update on anti-NMDA receptor  encephalitis for neurologists and psychiatrists: mechanisms and models. Lancet Neurol. 2019 Nov;18(11):1045-1057. doi: 10.1016/S1474-4422(19)30244-3.

van Sonderen A, Petit-Pedrol M, Dalmau J, Titulaer MJ. The value of LGI1, Caspr2 and voltage-gated potassium channel antibodies in encephalitis. Nat Rev Neurol. 2017 May;13(5):290-301. doi: 10.1038/nrneurol.2017.43.
 

Autoimmune Epilepsy

Vogrig A, Joubert B, André-Obadia N, Gigli GL, Rheims S, Honnorat J. Seizure specificities in patients with antibody-mediated autoimmune encephalitis. Epilepsia. 2019 Aug;60(8):1508-1525. doi: 10.1111/epi.16282.
 

MOG-Associated Syndromes

Reindl M, Waters P. Myelin oligodendrocyte glycoprotein antibodies in neurological disease. Nat Rev Neurol. 2019 Feb;15(2):89-102. doi:10.1038/s41582-018-0112-x.
 

Autoimmune Movement Disorders

Balint B, Vincent A, Meinck HM, Irani SR, Bhatia KP. Movement disorders with neuronal antibodies: syndromic approach, genetic parallels and pathophysiology. Brain. 2018 Jan 1;141(1):13-36. doi: 10.1093/brain/awx189.
 

Immune Checkpoint Inhibitors (ICIs)-associated neurological complications

Graus F, Dalmau J. Paraneoplastic neurological syndromes in the era of immune-checkpoint inhibitors. Nat Rev Clin Oncol. 2019 Sep;16(9):535-548. doi:10.1038/s41571-019-0194-4.

Perrinjaquet C, Desbaillets N, Hottinger AF. Neurotoxicity associated with cancer immunotherapy: immune checkpoint inhibitors and chimeric antigen receptor T-cell therapy. Curr Opin Neurol. 2019 Jun;32(3):500-510. doi:10.1097/WCO.0000000000000686.

Dalakas MC. Neurological complications of immune checkpoint inhibitors: what happens when you 'take the brakes off' the immune system. Ther Adv Neurol Disord. 2018 Sep14;11:1756286418799864. doi: 10.1177/1756286418799864.
 

Autoimmune Sleep Disorders

Bassetti CLA, Adamantidis A, Burdakov D, Han F, Gay S, Kallweit U, Khatami R, Koning F, Kornum BR, Lammers GJ, Liblau RS, Luppi PH, Mayer G, Pollmächer T, Sakurai T, Sallusto F, Scammell TE, Tafti M, Dauvilliers Y. Narcolepsy – clinical spectrum, aetiopathophysiology, diagnosis and treatment. Nat Rev Neurol. 2019 Sep;15(9):519-539. doi: 10.1038/s41582-019-0226-9.

Barateau L, Dauvilliers Y. Recent advances in treatment for narcolepsy. Ther Adv Neurol Disord. 2019 Sep 26;12:1756286419875622. doi:10.1177/1756286419875622.
 

HLA in autoimmune neurological syndromes

Muñiz-Castrillo, S., Vogrig, A. & Honnorat, J. Associations between HLA and autoimmune neurological diseases with autoantibodies. Autoimmun Highlights 11, 2 (2020). https://doi.org/10.1186/s13317-019-0124-6

 

Multiple Sclerosis

Sastre-Garriga J, Pareto D, Battaglini M, Rocca MA, Ciccarelli O, Enzinger C, Wuerfel J, Sormani MP, Barkhof F, Yousry TA, De Stefano N, Tintoré M, Filippi M, Gasperini C, Kappos L, Río J, Frederiksen J, Palace J, Vrenken H, Montalban X, Rovira À; MAGNIMS study group. MAGNIMS consensus recommendations on the use of brain and spinal cord atrophy measures in clinical practice. Nat Rev Neurol. 2020 Feb 24. doi: 10.1038/s41582-020-0314-x.

Derfuss T, Mehling M, Papadopoulou A, Bar-Or A, Cohen JA, Kappos L. Advances in oral immunomodulating therapies in relapsing multiple sclerosis. Lancet Neurol. 2020 Feb 11. pii: S1474-4422(19)30391-6. doi:10.1016/S1474-4422(19)30391-6.

Ontaneda D, Tallantyre E, Kalincik T, Planchon SM, Evangelou N. Early highly effective versus escalation treatment approaches in relapsing multiple sclerosis. Lancet Neurol. 2019 Oct;18(10):973-980. doi: 10.1016/S1474-4422(19)30151-6.
 

CIDP

Alessandro L, Pastor Rueda JM, Wilken M, Querol L, Marrodán M, Acosta JN, Rivero A, Barroso F, Farez MF. Differences between acute-onset chronic inflammatory demyelinating polyneuropathy and acute inflammatory demyelinating polyneuropathy in adult patients. J Peripher Nerv Syst. 2018 Sep;23(3):154-158. doi: 10.1111/jns.12266.

 

Gut microbiota in neuroimmunology

Cryan JF, O'Riordan KJ, Sandhu K, Peterson V, Dinan TG. The gut microbiome in neurological disorders. Lancet Neurol. 2020 Feb;19(2):179-194. doi:10.1016/S1474-4422(19)30356-4.

Boziki MK, Kesidou E, Theotokis P, Mentis AA, Karafoulidou E, Melnikov V, Sviridova A, Rogovski V, Boyko A, Grigoriadis N. Microbiome in MS; where are we, what we know and do not know. Brain Science 2020 Apr 14; 10(4). pii: E234. doi: 10.3390/brainsci10040234

Consensus review: A consensus review on the development of palliative care for patients with chronic and progressive neurological disease.

Opinion: The role of palliative care in patients with neurological diseases

Review: End of life care in long term neurological conditions: a framework for implementation.

Cordonnier C et al. Intracerebral haemorrhage: current approaches to acute management. 2018 Lancet
PMID 30319113

Zerna C et al. Current practice and future directions in the diagnosis and acute treatment of ischaemic stroke. 2018 Lancet
PMID 30319112

Rodrigues FB et al. Endovascular treatment versus medical care alone for ischaemic stroke: systematic review and meta-analysis. 2016, BMJ
PMID 27091337

Wang Y et al. Acute dual antiplatelet therapy for minor ischaemic stroke or transient ischaemic attack. 2019, BMJ
PMID 30819687

Seiffge DJ et al. Timing of anticoagulation after recent ischaemic stroke in patients with atrial fibrillation. 2019, Lancet Neurology
PMID 30415934

Wardlaw JM et al. Small vessel disease: mechanisms and clinical implications. 2019, Lancet Neurology
PMID 31097385

Saver JL et al. Patent Foramen Ovale Closure Versus Medical Therapy for Cryptogenic Ischemic Stroke. 2018, Stoke
PMID 29760277

Orrapin S et al. Carotid endarterectomy for symptomatic carotid stenosis. 2017, Cochrane Database Syst Rev
PMID 28590505

Hart RG et al. Embolic Stroke of Undetermined Source: A Systematic Review and Clinical Update. 2017, Stroke
PMID 28265016

Ekker MS et al. Epidemiology, aetiology, and management of ischaemic stroke in young adults. 2018, Lancet Neurology
PMID 30129475