Neurology Updates

Neurology Updates

Here you will find regular scientific news from our Scientific Panels. We cover all areas of neurology, including rare diseases. The most recent news are displayed below. You will find all news of different areas sorted into the subsections of the respective scientific panel. Enjoy reading!

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| Rare Neurological Diseases  

Serum α-synuclein seeds as a biomarker for synucleinopathies

A modified RT-QuIC assay combined with immunoprecipitation for the detection of α-synuclein fibrils appears to be a good blood biomarker for…

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Created by João Durães

| Neuro-ophthalmology and -otology  

The Semont-Plus is superior to the regular Semont and Epley maneuvers for the treatment of posterior canal benign paroxysmal positional vertigo

In two randomized prospective trials the time until recovery in posterior canal BPPV was significantly reduced by the Semont-Plus maneuver in…

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Created by Michael Strupp

| Neuroscience/ Translational neurology  

The first clinical trial with intrathecally transplanted neural stem-cells for progressive multiple sclerosis

Genchi et al. reported the first single-center phase 1 clinical trial assessing safety of intrathecally transplanted human fetal neural progenitor…

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Created by Radu Tanasescu

| Coma & Chronic Disorders of Consciousness  

Long-term clinical evolution of patients with prolonged disorders of consciousness due to severe anoxic brain injury: A meta-analytic study

Systematic review and meta-analysis addressing long-term clinical evolution of patients with prolonged Disorders of Consciousness due to severe anoxic…

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Created by Anna Estraneo

| Epilepsy  

Stereotactic EEG, intraoperative electrocorticography and brief potentially ictal rhythmic discharges (BIRDs)

We highlight recent reviews concerning stereotactic EEG, intraoperative electrocorticography and brief potentially ictal rhythmic discharges (BIRDs).

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Created by Ronan McGinty

| Neuroimmunology  

New definitions for an old disease: the newly proposed diagnostic criteria for Optic Neuritis Comment on: Diagnosis and classification of optic neuritis.

Newly proposed diagnostic criteria for optic neuritis renovate the clinical and research scenario and facilitate patients’ management

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Created by Matteo Gastaldi

| Neuroimmunology  

Autoimmune Encephalitis: balance between under and overestimation Comment on: Autoimmune encephalitis misdiagnosis in adults

A recent study dissects the causes for misdiagnosis of neurodegenerative and psychiatric conditions as autoimmune encephalitis, providing helpful…

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Created by Matteo Gastaldi

| Rare Neurological Diseases  

Omaveloxolone approved by FDA for Friedrich ataxia

The FDA has approved Omaveloxolone for the treatment of Friedrich ataxia (FA). Omaveloxone improved neurological function assessed with the modified…

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Created by João Durães

| Neuroscience/ Translational neurology | Rare Neurological Diseases  

Complement-dependent and -independent pathomechanisms of myelin oligodendrocyte glycoprotein (MOG)-Abs: implications for therapeutic strategies in MOG-antibody-associated disease (MOGAD)

Mader et al. dissect the MOG IgG effector mechanisms that characterize MOG-antibody-associated disease. FcR pathway mediates the MOG-Abs enhanced…

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Created by Marina Boziki

| Sleep disorders  

What Is the Role of the Cerebellum During Sleep?

The cerebellum is shown to be involved in sleep regulation by modulating sleep-wake cycles with the integrating sensory, motor, and cognitive…

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Created by Luca Baldelli

| Rare Neurological Diseases | Sleep disorders  

A new tool for screening Narcolepsy in children: the Pediatric Narcolepsy Screening Questionnaire (PNSQ)

The study validated a screening questionnaire for pediatric narcolepsy, which showed high sensitivity and specificity in identifying affected…

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Created by Luca Baldelli

| Sleep disorders  

Progression models for iRBD phenoconversion: unity is strength

This multicenter study identified the strongest progressors among predictive biomarkers of neurodegeneration in individuals with iRBD and tried to…

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Created by Luca Baldelli