Knowledge Distillery

In this trial, the authors assigned COVID-19 patients to receive either one unit of convalescent plasma with a high titer of antibodies against severe…

Peginterferon lambda for the treatment of outpatients with COVID-19: a phase 2, placebo-controlled randomised trial

This trial tested the safety and efficacy of levosimendan in improving supine slow vital capacity after 12 weeks of treatment in 496 people with…

The objective of this multicenter randomized clinical trial was to assess whether helmet noninvasive ventilation can increase the days free of…

The objective of this randomised, double blind, placebo controlled trial was to determine if inhaled and intranasal ciclesonide are superior to…

The objective of this randomized clinical trial was to determine whether hydroxychloroquine or lopinavir-ritonavir reduces hospitalization among…

A new variant of SARS-CoV-2, B.1.1.7, emerged as the dominant cause of COVID-19 disease in the UK from November, 2020. In this article the authors…

In this phase 1, double-blind, placebo-controlled, block-randomised trial the authors aimed to assess the safety and immunogenicity of an…

CoV2 preS dTM is a stabilised pre-fusion spike protein vaccine produced in a baculovirus expression system being developed against SARS-CoV-2. In this…

This study randomly assigned participants who were enrolled within 96 hours after a household contact received a diagnosis of SARS-CoV-2 infection to…

This study evaluates the efficacy and safety of baricitinib in combination with standard of care for the treatment of hospitalised adults with…

The objective of this study was to assess whether anticoagulant or antiplatelet therapy can safely reduce major adverse cardiopulmonary outcomes among…