Knowledge Distillery

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| Miscellaneous  

RETRACTION: Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis.

On June 3, we published in the Breaking News section of this site the article entitled “Hydroxychloroquine or chloroquine with or without a macrolide…

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Myth-busting

Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis

In this article, just published in Lancet, the authors report an analysis of multinational registry data on the use of hydroxychloroquine or…

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Myth-busting

Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial.

The objective of this parallel, double-masked, randomized, phase IIb clinical trial, was to evaluate the safety and efficacy of 2 chloroquine…

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Myth-busting

Headaches Associated with Personal Protective Equipment – A Cross-sectional Study Amongst Frontline Healthcare Workers During COVID-19 (HAPPE Study)

COVID-19 AND NEUROLOGY During the COVID-19 outbreak, frontline healthcare workers were mandated to wear personal protective equipment (PPE) while…

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Myth-busting

| Observational study: prospective longitudinal cohort  

Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study

Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective…

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Myth-busting

| Randomised double-blinded placebo-controlled trial  

Effect of Early Treatment With Hydroxychloroquine or Lopinavir and Ritonavir on Risk of Hospitalization Among Patients With COVID-19 The TOGETHER Randomized Clinical Trial

The objective of this randomized clinical trial was to determine whether hydroxychloroquine or lopinavir-ritonavir reduces hospitalization among…

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Myth-busting

| Randomised double-blinded placebo-controlled trial  

Effect of Early Treatment With Hydroxychloroquine or Lopinavir and Ritonavir on Risk of Hospitalization Among Patients With COVID-19 The TOGETHER Randomized Clinical Trial

Data on the efficacy of hydroxychloroquine or lopinavir-ritonavir for the treatment of high-risk outpatients with COVID-19 in developing countries are…

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Myth-busting

| Observational study: prospective longitudinal cohort  

Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study

Early in the pandemic it was suggested that pre-existing use of non-steroidal anti-inflammatory drugs (NSAIDs) could lead to increased disease…

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Myth-busting