Correlates of critical illness-related encephalopathy predominate postmortem COVID-19 neuropathology

In this paper recently published in Acta Neuropathologica the authors report on neuropathological findings from autopsy for a study cohort of seven COVID-19 patients, all of whom were positive for SARS-CoV-2 by nasopharyngeal swab testing, and compare their observations with those made in a SARS-CoV-2 negative control autopsy cohort comprising individuals with non-septic and systemic inflammatory/septic clinical courses.

 

In this paper recently published in Acta Neuropathologica the authors report on  neuropathological findings from autopsy for a study cohort of seven COVID-19 patients, all of whom were positive for SARS-CoV-2 by nasopharyngeal swab testing, and compare their observations with those made in a SARS-CoV-2 negative control autopsy cohort comprising individuals with non-septic and systemic inflammatory/septic clinical courses. The authors underline that their observations suggest that specific SARS-CoV-2 induced neuropathological abnormalities are absent in the majority of COVID-19 patients.

https://doi.org/10.1007/s00401-020-02213-y