Knowledge Distillery

The objective of this prospective, open-label, randomised clinical trial, was to evaluate the effect of treatment with colchicine on cardiac and…

In this study recently published in the New England Journal of Medicine, the authors conducted a phase 1, dose-escalation, open-label trial including…

In this controlled, open-label trial recently published in the New England Journal of Medicine, the authors randomly assigned patients who were…

In this article the authors assessed whether azithromycin is effective in reducing hospital admission in patients with mild-to-moderate COVID-19.

In this article the authors conducted a single-center, open-label, non-randomized, Phase 1 trial in India between July 2020 and October 2020.

This phase 3 trial randomly assigned a cohort of patients with mild or moderate COVID-19 who were at high risk for progression to severe disease to…

Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an…

Discontinuation versus continuation of renin-angiotensin-system inhibitors in COVID-19 (ACEI-COVID): a prospective, parallel group, randomised,…

In this paper, just published in Lancet, the authors performed a dose-escalation, single-centre, open-label, non-randomised, phase 1 trial of a…

In this open-label, multicentre, randomised clinical trial, recently published in JAMA, the authors evaluate the efficacy and adverse effects of…

Azithromycin for community treatment of suspected COVID-19 in people at increased risk of an adverse clinical course in the UK (PRINCIPLE): a…

Interleukin-6 Receptor antagonists in critically ill patients with COVID-19