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| Randomised double-blinded placebo-controlled trial  

High-flow nasal oxygen is recommended as initial treatment for acute hypoxemic respiratory failure and is widely applied in patients with COVID-19.

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| Observational study: prospective longitudinal cohort  

No standard therapy, including anticoagulation regimens, is currently recommended for coronavirus disease 2019.

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| Interventional study with open label/non-randomised methodology  

Many patients with COVID-19 have been treated with plasma containing anti-SARS-CoV-2 antibodies

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