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SARS-CoV-2 Related Encephalitis: MRI Pattern of the Olfactory Tract Involvement

SARS-CoV-2 Related Encephalitis: MRI Pattern of the Olfactory Tract Involvement

 

In this case report recently published in Neurology, the authors report the case of a 96-year-old female patient admitted to the Emergency Room with generalised epileptic seizures and fever followed by left hemiparesis. Two days before admission she started with anosmia, dysgeusia and behavioural dysexecutive syndrome. CSF analysis yielded 8 leukocytes/mm3 (75% polymorphonuclear neutrophilic cells) and was negative for SARS-CoV-2 PCR. Brain MRI revealed hyperintensity of the olfactory tracts on T2 FLAIR and diffusion-weighted imaging. Ten days after admission, SARS-CoV-2 serology returned positive, thus supporting a SARS-CoV-2 related encephalitis.

DOI: https://doi.org/10.1212/WNL.0000000000011150