Myasthenia Gravis Associated With SARS-CoV-2 Infection

In this paper, recently published in Annals of Internal Medicine, the authors describe 3 patients without previous neurological or autoimmune disorders who were diagnosed with myasthenia gravis after the onset of coronavirus disease 2019 (COVID-19).

In this paper, recently published in Annals of Internal Medicine, the authors describe 3 patients without previous neurological or autoimmune disorders who were diagnosed with myasthenia gravis after the onset of coronavirus disease 2019 (COVID-19). Symptoms of myasthenia gravis appeared within 5 to 7 days after fever onset in all 3 patients, and the time from presumed infection with SARS-CoV-2 to the beginning of myasthenia gravis symptoms was consistent with the time from infection to symptoms in other neurologic disorders triggered by infections. All patients improved after pyridostigmine bromide and prednisone treatment (patient 1); 1 cycle of intravenous immunoglobulin treatment (patient 2) and plasmapheresis sessions (patient 3).

https://doi.org/10.7326/L20-0845