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| Observational study: prospective longitudinal cohort  

The objective of this prospective, multicentre, observational cohort study was to assess neurological manifestations and quality of life (QoL) three…

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| Literature Review  

This review focuses on new evidence supporting the global immunization strategy for MS patients receiving disease-modifying drugs (DMDs), including…

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| Miscellaneous  

Acute delirium and other neuropsychiatric symptoms have frequently been reported in COVID-19 patients and are variably referred to as acute…

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| Case series/case reports  

Whilst respiratory failure in COVID-19 arises from severe interstitial lung involvement, SARS-CoV-2 likely spreads also through the nervous system.

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| Miscellaneous  

The SARS-CoV-2 spike (S) glycoprotein contains an immunodominant receptor-binding domain (RBD) targeted by most neutralizing antibodies (Abs) in…

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| Miscellaneous  

The deployment of a vaccine that limits transmission and disease likely will be required to end the COVID-19 pandemic.

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| Case series/case reports  

Continued uncontrolled transmission of the SARS-CoV-2 in many parts of the world is creating the conditions for significant virus evolution.

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| Expert opinion  

Since the initial reports of a cluster of pneumonia cases of unidentified origin in Wuhan, China, in December 2019, the novel coronavirus that causes…

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| Miscellaneous  

To circumvent time-consuming clinical trials, testing whether existing drugs are effective inhibitors of SARS-CoV-2 , has led to the discovery of…

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| Randomised double-blinded placebo-controlled trial  

Control of the global COVID-19 pandemic will require the development and deployment of safe and effective vaccines.

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| Case series/case reports  

The objective of this prospective uncontrolled cohort study was to describe the consequences at 4 months in patients hospitalized for COVID-19.

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| Case series/case reports  

Extensive global sampling and sequencing of the pandemic virus SARS-CoV-2 have enabled researchers to monitor its spread, and to identify concerning…

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| Miscellaneous  

A novel SARS-CoV-2 variant, VOC 202012/01 (lineage B.1.1.7), emerged in southeast England in November 2020 and is rapidly spreading toward fixation.

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| Miscellaneous  

Substitution for aspartic acid by glycine at position 614 in the spike (S) protein of severe acute respiratory syndrome coronavirus 2 appears to…

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| Case series/case reports  

SARS-CoV-2 infections and hospital admissions for COVID-19 increased rapidly in the South East region of England in November and December 2020,…

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| Observational study: prospective longitudinal cohort  

The efficacy of two injections of the SARS-CoV-2 spike mRNA vaccines (BNT162b2 [Pfizer] and mRNA-1273 [Moderna]) in preventing symptomatic SARS-CoV-2…

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| Observational study: prospective longitudinal cohort  

As mass vaccination campaigns against COVID-19 commence worldwide, vaccine effectiveness needs to be assessed for a range of outcomes across diverse…

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| Randomised double-blinded placebo-controlled trial  

Assessment of the safety and efficacy of vaccines against the SARS-CoV-2 in different populations is essential, as is investigation of the efficacy…

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| Case series/case reports  

Coronavirus disease have been reported to be associated with several neurological manifestations such as stroke, Guillain-Barré syndrome,…

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| Miscellaneous  

The coronavirus spike glycoprotein, located on the virion surface, is the key mediator of cell entry and the focus for development of protective…

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| Cross-sectional case-control studies  

The impact of the COVID‐19 pandemic on PD patients is yet to be determined.

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| Cross-sectional case-control studies  

The authors conducted a longitudinal case-control 18F-FDG-PET study in patients diagnosed with COVID-19-related encephalopathy.

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| Cross-sectional case-control studies  

The effects of the COVID‐19 pandemic on telemedical care have not been described on a national level. Thus, the authors investigated the medical…

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| Cross-sectional case-control studies  

This nationwide study assessed the impact of the pandemic on stroke hospitalisation rates, patient characteristics, and 30‐day case fatality rates.

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| Case series/case reports  

Emergence of SARS-CoV-2 causing COVID-19 prompted the need to gather information on clinical outcomes and risk factors associated with morbidity and…

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| Case series/case reports  

The aim of this retrospective, international multicenter study was to assess the association between abnormal findings on chest and brain imaging in…

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| Literature Review  

The purpose of this review was to provide an overview on current knowledge of neurological symptoms and complications of COVID-19, and to suggest…

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| Observational study: prospective longitudinal cohort  

Studies suggest an increased risk of adverse outcomes among patients with acute ischemic stroke (AIS) and COVID-19.

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| Cross-sectional case-control studies  

The objective of this matched cohort study was to establish whether there is any change in mortality from infection with a new variant of SARS-CoV-2 ,…

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| Miscellaneous  

Most human monoclonal antibodies (mAbs) neutralizing SARS-CoV-2 recognize the spike (S) protein receptor-binding domain and block virus interactions…

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| Miscellaneous  

SARS-CoV-2 has currently precipitated the COVID-19 global health crisis. The authors of this article developed a medium-throughput drug screening…

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| Miscellaneous  

COVID-19 pandemic is the third zoonotic coronavirus (CoV) outbreak of the century after SARS in 2003 and MERS since 2012.

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| Cross-sectional case-control studies  

COVID-19 affects the nervous system in adult patients. The spectrum of neurologic involvement in children and adolescents is unclear. The objective …

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| Cross-sectional case-control studies  

Refinement of criteria for multisystem inflammatory syndrome in children (MIS-C) may inform efforts to improve health outcomes.

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| Case series/case reports  

There is evidence of central nervous system impairments associated with COVID-19 infection, including encephalopathy.

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| Meta-analysis Systematic Review  

The objective of this article was to assess clinical outcomes with convalescent plasma treatment vs placebo or standard of care in peer-reviewed and…

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| Cross-sectional case-control studies  

SARS-CoV-2 lineage B.1.1.7, a variant first detected in the UK in September 2020, has spread to multiple countries worldwide.

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| Interventional study with open label/non-randomised methodology  

Azithromycin, an antibiotic with potential antiviral and anti-inflammatory properties, has been used to treat COVID-19, but evidence from community…

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| Cross-sectional case-control studies  

Self-report data on mental distress indicate a deterioration of population mental health in many countries during the COVID-19 pandemic.

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| Interventional study with open label/non-randomised methodology  

The efficacy of interleukin-6 receptor antagonists in critically ill patients with COVID-19 is unclear. In this article the authors evaluated…

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| Randomised double-blinded placebo-controlled trial  

COVID-19 is associated with immune dysregulation and hyperinflammation, including elevated interleukin-6 levels. The use of tocilizumab, a monoclonal…

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